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Rare presentation of cryptococcal meningitis in an immunocompetent patient
  1. Ahmed Khattab,
  2. Sunita Patruni and
  3. Mary L Sealey
  1. Department of Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA
  1. Correspondence to Dr Ahmed Khattab, ahmedkhattab47{at}


Cryptococcal meningitis is an opportunistic infection predominantly affecting immunocompromised patients but rarely can affect the immunocompetent. We describe a 53-year-old Caucasian man who presented complaining of a 2-week history of severe bilateral eye pain and diplopia. His only known risk factor was that he lived in a horse farm and recently shot bats and pigeons in his barn. He visited an outside hospital during this time without a diagnosis established. After further deliberation, we obtained a lumbar puncture (LP) which revealed an opening pressure (OP) of 27 cm H2O. Cerebrospinal fluid (CSF) and fungal cultures confirmed the presence of Cryptococcus neoformans. The patient was diagnosed with C. neoformans-mediated meningoencephalitis and was initiated on the appropriate induction anti-fungal therapy. This case emphasises the need for clinicians to remain vigilant and consider cryptococcal meningitis in immunocompetent individuals even when classic symptoms of meningitis are absent.

  • cryptococcus
  • cryptococcosis
  • meningitis
  • exposures
  • visual pathway

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  • Contributors AK conceived the presented idea and AK, SP and MLS were directly involved in the patient’s care. AK and SP were involved in the data collection, analysis and interpretation. AK, SP and MLS were all involved in the literature review. AK and SP drafted the article and MLS was involved in critical revision of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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