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Thrombolysis for deep venous thrombosis associated with inferior vena cava agenesis in a young patient
  1. Selma Regina de Oliveira Raymundo,
  2. Vanessa Souza Cabral,
  3. Raissa Fortuna Cavalieri and
  4. Fernando Reis Neto
  1. Cardiologia e Cirugia Vascular, Faculdade de Medicina de Sao Jose do Rio Preto, São José do Rio Preto, Brazil
  1. Correspondence to Dr Selma Regina de Oliveira Raymundo, selma_ray{at}


Malformations of inferior vena cava (IVC) as agenesis are a rare congenital anomaly and cause of deep venous thrombosis (DVT) of lower limbs and should be investigated in young patients of unknown aetiology. Treatment with mechanical thrombectomy and thrombolysis can be considered in certain cases of DVT, promoting rapid clot removal, and has also been shown to be an effective treatment in acute DVT. We present a case of acute lower limb DVT associated with IVC agenesis in which Alteplase thrombolysis was used and thrombus aspiration with catheter bilaterally, with subsequent angioplasty of the common and external iliac, obtaining satisfactory results.

  • venous thromboembolism
  • portal vein
  • vascular surgery
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  • Contributors Substantial contributions to the conception or design of the work, or the acquisition, analysis or interpretation of data: SRdOR, VSC, FRN and RFC. Drafting the work or revising it critically for important intellectual content: SRdOR, VSC and FRN. Final approval of the version published: SRdOR, VSC, FRN and RFC. Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: SRdOR, VSC, FRN and RFC.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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