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Unexpected outcome (positive or negative) including adverse drug reactions
CASE REPORT
Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis
  1. Andrew Beverstock1 and
  2. Alison Kelly2
  1. 1 Department of Paediatric Orthopaedics, Bristol Royal Hospital for Children, Bristol, UK
  2. 2 Department of Paediatric Rheumatology, Bristol Royal Hospital for Children, Bristol, UK
  1. Correspondence to Dr Andrew Beverstock, andrew.beverstock{at}uhbristol.nhs.uk

Abstract

We report the case of a 6-year-old girl with juvenile idiopathic arthritis and anterior uveitis who was treated with two doses of intravenous methylprednisolone for acute arthritis. She developed severe ocular hypertension (intraocular pressures (IOPs) of 54 mm Hg in the right eye and 61 mm Hg in the left eye) requiring inpatient therapy with intravenous acetazolamide. The normal range of values for IOP is 12–22 mm Hg. This severe case of acute intraocular hypertension due to systemic steroids highlights the need to consider monitoring of IOPs for children on high-dose topical and systemic steroids with risk factors for raised IOP.

  • paediatrics (drugs and medicines)
  • paediatrics
  • rheumatology
  • glaucoma

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/bcr-2019-229803

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    Footnotes

    • Contributors AB wrote initial draft. AK amended the draft and approved the final version.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.

    • Patient consent for publication Parental/guardian consent obtained.