Article Text

Download PDFPDF
Holoprosencephaly or severe hydrocephalus: T1 sequence tells the story
  1. Fariba Zarei,
  2. Pooya Iranpour and
  3. Sara Haseli
  1. Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  1. Correspondence to Dr Pooya Iranpour, pooya.iranpour{at}


Intracranial lipoma is a relatively rare benign lesion. Many are incidental findings; however, some others may present with headache, hydrocephalus or other neurological symptoms; thus, correct diagnosis of this condition is important. These lesions are of high signal intensity on T2-weighted MRI and especially those close to cerebrospinal fluid (CSF) spaces, can easily be overlooked in the background of high signal intensity of CSF. Here, we present a case of tectal lipoma, with subsequent severe hydrocephalus and absence of septum pellucidum which was initially misinterpreted as a form of holoprosencephaly, due to inadequate attention to T1-weighted images.

  • neurology
  • neuroimaging
  • radiology

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors FZ has provided the case and images and has reviewed the article and contributed to the final version of the manuscript. PI and SH have designed the project and contributed in preparing the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/guardian consent obtained.