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Primary non-Hodgkin’s lymphoma of the vagina (PNHLV): a gynaecologist’s enigma!
  1. Nanak Bhagat1,
  2. Pallavi Kalkur2 and
  3. Sanjaya Kalkur1
  1. 1 Obstetrics and Gynaecology, Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, UK
  2. 2 Haematology, Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, UK
  1. Correspondence to Dr Nanak Bhagat, nanakbhagat{at}


Primary lymphoma of the female genital tract is very rare, particularly those presenting primarily in the vagina are even rarer. We report a case of a 60-year-old woman who presented with generalised abdominal pain, vaginal discharge and a thickening of the posterior vaginal wall. Prompt radiological investigations and biopsy led to early diagnosis and appropriate treatment. Complete metabolic remission was obtained with three cycles of chemotherapy and radiotherapy. This case highlights the need for increasing the awareness about lymphomas presenting as vaginal lesion(s) and for clinicians to keep an open mind when working up such patients.

  • obstetrics, gynaecology and fertility
  • cancer—see oncology
  • oncology

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  • Contributors SK conceived the idea about the article. NB, PK and SK have gone on to write and edit the article subsequently.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.