Article Text

PDF
CASE REPORT
Xanthoma disseminatum with neurological involvement and optic atrophy: improvement with cladribine
  1. Suman Patra,
  2. Saurabh Bhatia,
  3. Binod K Khaitan and
  4. Neetu Bhari
  1. Dermatology and Venereology, AIIMS, New Delhi, India
  1. Correspondence to Dr Neetu Bhari, drntbhari{at}gmail.com

Abstract

A 9-year-old boy presented with multiple hyperpigmented papules over flexors with polyuria, polydipsia and progressive loss of vision. Histopathology of papule suggested a diagnosis of non-Langerhans cell histiocytosis and systemic evaluation showed central diabetes insipidus and optic atrophy. With a diagnosis of xanthoma disseminatum with significant neurological involvement, he received cladribine therapy and showed significant improvement in both cutaneous and nervous system lesions.

  • dermatology
  • paediatrics
View Full Text

Statistics from Altmetric.com

Footnotes

  • Contributors SP, SB, BKK and NB prepared, reviewed and finalised the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/Guardian consent obtained.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.