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First-dose idarubicin cardiomyopathy: a case of new heart failure after induction chemotherapy for acute myeloid leukaemia
  1. Zarir Ahmed1,
  2. Elizabeth Davaro2,
  3. Jacqueline Batanian2 and
  4. Nilesh Verma3
  1. 1 Department of Internal Medicine, St Louis University, St Louis, Missouri, USA
  2. 2 Department of Pathology, St Louis University, St Louis, Missouri, USA
  3. 3 Department of Hematology Oncology, St Louis University Hospital, St Louis, Missouri, USA
  1. Correspondence to Dr Zarir Ahmed, zarirmed{at}


Anthracyclines are an effective chemotherapy agent. However, very few cases of idarubicin-induced cardiomyopathy exist. Herein, we describe a case of first-dose idarubicin-related acute heart failure in a woman with a history of myelodysplastic syndrome converted to acute myeloid leukaemia.

  • cardiovascular system
  • heart failure
  • chemotherapy
  • haematology (incl blood transfusion)
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  • Contributors ZA wrote the manuscript. ED obtained and formatted the pathology slides. JB obtained the karyotoype slide. NV critically revised the paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.

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