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Familial hypertriglyceridaemia and type 2 diabetes in pregnancy: prevention of acute pancreatitis with diet control and omega-3 fatty acids
  1. Melissa Ong1,
  2. Lynne Jerreat2 and
  3. Aisha Hameed2
  1. 1 Faculty of Life Sciences and Medicine, King’s College London School of Medical Education, London, UK
  2. 2 Department of Obstetrics and Gynaecology, Princess Royal University Hospital, Orpington, UK
  1. Correspondence to Melissa Ong,{at}


Acute pancreatitis in pregnancy is rare and can be caused by hypertriglyceridaemia. The management of hypertriglyceridaemia in pregnancy is complex and challenging as many lipid-lowering medications have been found to be unsafe in pregnancy. Patients who present with hypertriglyceridaemia commonly have multiple risk factors such as, diabetes, alcohol excess and hypothyroidism which pose a greater challenge to the management of these patients. We present a case of a 31-year-old woman presenting with familial hypertriglyceridaemia and type 2 diabetes mellitus in her third pregnancy. She had an uneventful pregnancy with the use of omega-3 fatty acids nutritional support, low-fat diet and tight glucose control with insulin and metformin.

  • diabetes
  • lipid disorders
  • diet
  • pregnancy
  • vitamins and supplements

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  • Contributors MO wrote the initial manuscript and performed literature search. LJ and AH expanded on this and also performed literature search. MO and AH contributed to the final editing of the manuscript. All authors reviewed the final revision and approved the version to be published.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.