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A 40-year-old male patient presented with recent-onset atypical retrosternal chest pain, having low to intermediate probability of coronary artery disease. CT angiography (CTA) was performed to evaluate the coronaries, which revealed chronic total occlusion (CTO) of the left anterior descending (LAD) artery distal to the origin of the second diagonal branch (D2) with reformation of a distal LAD artery. The D2 was tortuous and coursing along the left ventricular (LV) epicardial surface and seen to supply the distal LAD artery myocardial territory via an epicardial collateral at the LV apex. The LAD artery segment distal to the occlusion was good sized and showed no significant disease (figure 1). A mixed plaque in the proximal LAD artery causing moderate stenosis was also noted along with diffuse significant atherosclerotic disease involving the right coronary artery (RCA) and left circumflex (LCx) artery.
The most commonly observed collaterals in cases of CTO of LAD artery are from the septal branch of the posterior descending artery, right atrial and right ventricular branches of RCA and obtuse marginal branches of LCx artery.1 However, in our case, the sole collateral reforming the LAD artery was from the hypertrophied D2 branch of the LAD itself arising proximal to the occluded segment, understandably termed an ‘auto-collateral’. The other more commonly observed collaterals were not present owing to significant disease in the RCA and LCx artery and hence, the epicardial collateral from D2 might have increased in size according to the perfusion gradients. Identification of this large collateral on CTA will have a significant impact on the planning of any retrograde percutaneous intervention when indicated. Having a beforehand knowledge of the pathological anatomy would allow an informed decision regarding approach to revascularisation as well as optimum hardware selection, thus increasing the procedural efficacy.2 However, considering the limitations of CTA in optimally visualising small collaterals owing to suboptimal opacification of very small vessels, it should also be kept in mind that a subsequent catheter angiography may reveal other collateral pathways which may be safer or more appropriate for use during percutaneous intervention.
Commonly observed collaterals in cases of chronic total occlusion of left anterior descending artery are from the septal branch of the posterior descending artery, right atrial and right ventricular branches of right coronary artery and obtuse marginal branches of left circumflex artery.
In some cases, collaterals from the left anterior descending artery branches arising proximal to occlusion may reform it distal to the occlusion and are understandably termed ‘auto-collaterals’.
Identification of such large collaterals will have significant impact on the planning of any retrograde percutaneous intervention whenever indicated.
Contributors MSh, NNP, MSi and SK have participated sufficiently in the conception of the idea, development of the intellectual content, design, writing and final approval of the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Obtained.
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