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Man with epigastric pain and persistently elevated serum lipase
  1. Caroline Annette Erika Bachmeier and
  2. Adam Morton
  1. Queensland Diabetes and Endocrine Centre, Mater Misericordiae Brisbane Ltd, South Brisbane, Queensland, Australia
  1. Correspondence to Dr Caroline Annette Erika Bachmeier, carolinebachmeier{at}


Serum lipase and amylase are commonly requested in individuals presenting with abdominal pain for investigation of acute pancreatitis. Pancreatic hyperenzymaemia is not specific for acute pancreatitis, occurring in many other pancreatic and non-pancreatic conditions. Where persistent elevation of serum lipase and amylase occurs in the absence of a diagnosed cause or evidence of laboratory assay interference, ongoing radiological assessment for pancreatic disease is required for 24 months before a diagnosis of benign pancreatic hyperenzymaemia can be made. We report a case of a 71-year-old man with epigastric pain and elevated serum lipase levels. He was extensively investigated, but no pancreatic disease was detected. He is asymptomatic, but serum lipase levels remain elevated 18 months after his initial presentation.

  • diabetes
  • pancreas and biliary tract
  • pancreatitis

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  • Contributors AM and CAEB have both contributed significantly to the writing and editing of the manuscript. AM has reviewed our patient on numerous occasions in his role as an endocrinology consultant.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.