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CASE REPORT
Signet ring cell carcinoma of the rectum: atypical metastatic presentation
  1. Mariana Morales-Cruz1,
  2. Noel Salgado-Nesme1,
  3. Alicia Maybi Trolle-Silva2 and
  4. Jorge Humberto Rodríguez-Quintero3
  1. 1 Department of Colorectal Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Tlalpan, Mexico City, Mexico
  2. 2 Department of Pathology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Tlalpan, Mexico City, Mexico
  3. 3 Department of General Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Tlalpan, Mexico City, Mexico
  1. Correspondence to Dr Jorge Humberto Rodríguez-Quintero, huroqu90{at}gmail.com

Abstract

Colorectal cancer is the third most common cancer in the world and the fourth most common cause of death related to cancer. Signet ring cell carcinoma represents an uncommon histological type for rectal cancer with less than 1% of all rectal neoplasms. It usually behaves aggressively and has an inferior prognosis. We present the case of a young man diagnosed with signet ring cell rectal carcinoma. He underwent neoadjuvant therapy with partial response, had surgery with curative intent and showed local recurrence after only 3 months. Disease progression happened only weeks after recurrence with metastasis to vertebrae, extraocular muscles, bone marrow and skin. He is currently receiving palliative chemotherapy.

  • Colon cancer
  • Colorectal surgery
  • Signet-ring cell
  • Surgery
  • Oncologic surgery

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Footnotes

  • Contributors MM-C, NS-N, AMT-S and JHR-Q were responsible for planning of the case and conceived the original idea. MM-C, NS-N, AMT-S and JHR-Q wrote the manuscript. MM-C helped supervise and conduct the project. The design of the manuscript was done by NS-N and AMT-S. Acquiring of data was achieved by JHR-Q and acquiring and preparing of the images was done by MM-C, NS-N, AMT-S and JHR-Q. The interpretation of data was performed by MM-C, NS-N, AMT-S and JHR-Q. MM-C, NS-N, AMT-S and JHR-Q were directly involved in the treatment of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.

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