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Nephrotic range proteinuria and metabolic alkalosis in Takayasu arteritis
  1. Takahiro Tsuchida,
  2. Hiroyuki Yano,
  3. Yoshihiko Raita and
  4. Mitsuyo Kinjo
  1. Department of Internal Medicine, Okinawa Chubu Hospital, Uruma, Japan
  1. Correspondence to Dr Mitsuyo Kinjo, kinjomitsuyo{at}


Nephrotic range proteinuria and metabolic alkalosis are unusual findings in large vessel vasculitis. In this case, renovascular hypertension with unilateral renal artery stenosis in Takayasu arteritis was complicated by nephrotic range proteinuria. Symptoms resolved after angioplasty, although non-nephrotic proteinuria persisted. The renal pathology of Takayasu arteritis included focal glomerulosclerosis.

  • vasculitis
  • proteinurea
  • fluid electrolyte and acid-base disturbances

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  • Contributors TT wrote the manuscript, reviewed charts, collected data and summerised the findings. HY wrote manuscript, collected data and analysed the findings, edited images. YR reviewd charts, collected data and analysed pathological findings. MK contributed to overall writing, data analysis and discussion.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.