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CASE REPORT
Large paraspinal abscess as a complication of infliximab therapy in Crohn’s disease
  1. Nishani Nithianandan1,
  2. Michael J Loftus2,
  3. Paul D R Johnson2,3 and
  4. Patrick G P Charles1,2,3
  1. 1 Department of General Medicine, Austin Health, Heidelberg, Victoria, Australia
  2. 2 Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
  3. 3 Department of Medicine, University of Melbourne, Austin Health, Parkville, Victoria, Australia
  1. Correspondence to Dr Nishani Nithianandan, nishani.nithianandan{at}austin.org.au

Abstract

We report a 36-year-old man who developed a large epidural and paraspinal abscess as a complication of infliximab therapy being used for underlying Crohn’s disease. Cultures of the collection grew methicillin-susceptible Staphylococcus aureus, and treatment consisted of abscess drainage, prolonged intravenous and oral flucloxacillin and temporary withholding of his infliximab. While infection-related complications are well described with infliximab therapy, this is the first description of a large paraspinal abscess with epidural extension.

  • crohn’s disease
  • infection (neurology)
  • bone and joint infections
  • infections
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Footnotes

  • Contributors NN led case report conception and design, conducted data acquisition and analysis, drafted the manuscript and provides final approval of the version to be published. MJL made contributions to data acquisition, made critical revisions to the manuscript and provided final approval of the version to be published. PJ made contributions to case report conception, made critical revisions to the manuscript and provided final approval of the version to be published. PC led the case report conception and design, supervised data analysis, made critical revisions to the manuscript and provided final approval of the version to be published. All authors agreed to be accountable for all aspects of the work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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