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Breast MALT lymphoma and AL amyloidosis complicating Sjögren’s syndrome
  1. Nabil Belfeki,
  2. Salima Bellefquih and
  3. Anne Bourgarit
  1. Internal Medicine, Hopital Jean Verdier, Bondy, France
  1. Correspondence to Dr Nabil Belfeki, belfeki.nabil{at}


Marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) lymphomas of the breast with mammary amyloidosis are exceedingly rare entities. This report describes the case of women with long-standing Sjögren’s syndrome presenting with breast MALT lymphoma and amyloïd light-chain (AL) amyloidosis. Breast microcalcification needle biopsy made the positive diagnosis. This unusual finding should be kept in mind. It emphasises the need for careful clinical examination of nodes and extranodal organs supposedly affected in patients with autoimmune disease.

  • haematology (incl blood transfusion)
  • immunology
  • breast cancer

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  • Contributors NB, SB and AB: discussed this complex clinical case. We illustrated its complexity in the investigation part and discussed its scarcity in another part. NB: wrote the case with input of all authors. SB: performed the interpretation of the different biopsies. AB: supervised the management of the patient and the redaction of the report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.