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Neuromyelitis optica spectrum disorder and adenocarcinoma of ovary: a novel association
  1. Julie Sachdeva1,
  2. Ramandeep Bansal2,
  3. Aastha Takkar1 and
  4. Rajveer Singh1
  1. 1 Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India
  2. 2 Department of Gynecology and Obstetrics, Postgraduate Institute of Medical Education and Research, Chandigarh, Punjab, India
  1. Correspondence to Dr Rajveer Singh, rajveersaharan{at}


Paraneoplastic neuromyelitis optica spectrum disorder (NMOSD) is a rare clinical entity with less than 40 cases described in literature until today. Paraneoplastic NMOSD in association with adenocarcinoma of ovary has not been described yet. We present a case of paraneoplastic NMOSD in association with carcinoma ovary which improved following appropriate immunomodulation with pulse intravenous methylprednisolone and azathioprine.

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  • Contributors JS: drafting of manuscript and revision. RB: data collection, drafting of manuscript, review of literature. RS: drafting of manuscript and revision. AT: concept and revision of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/guardian consent obtained.