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Sweet syndrome induced by radiations during breast cancer treatment
  1. Luc Ollivier1,2,
  2. Emmanuelle Renaud3,4,5,
  3. Dominique Gouders2 and
  4. Patrice Plantin4
  1. 1 Radiotherapy, CHRU de Brest, Brest, France
  2. 2 Radiotherapy, Centre Hospitalier de Cornouaille, Quimper, Bretagne, France
  3. 3 Dermatology, CHRU de Brest, Brest, France
  4. 4 Dermatology, Centre Hospitalier de Cornouaille, Quimper, France
  5. 5 Medical Oncology, Centre Hospitalier Regional Universitaire, Brest, Bretagne, France
  1. Correspondence to Mr Luc Ollivier, lucm.ollivier{at}


During the follow-up of a woman treated by radiotherapy for an in situ carcinoma of her left breast, radio-induced skin lesions were diagnosed. They appeared not to be simple radiodermatitis but radio-induced Sweet syndrome. Discussions were led on the benefit of completing the last session of radiotherapy for such a low-grade malignancy while considering the risk of complication from radio-induced disease. General and local corticotherapy rapidly eradicated the fever and asthenia, while the skin lesions disappeared gradually. Moreover, biological improvement was noticed. The presented features of Sweet syndrome are almost similar in their initial phase to the radiodermatitis that is seen in common medical conditions.

  • dermatology
  • skin
  • breast cancer
  • radiotherapy
  • unwanted effects / adverse reactions

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  • LO and ER contributed equally.

  • DG and PP contributed equally.

  • Contributors LO followed the patient during the radiotherapy, detected that it was not a simple radio dermatitis, performed the literature review and wrote the article. ER took care of the patient during the hospitalisation, performed the punch biopsy, performed the literature review and wrote the article. DG confirmed that is was not a simple radio dermatitis, authorise to complete the radiotherapy, reviewed and commented the article. PP evoked the differential diagnosis, proposed the hospitalisation of the patient, made the dermatologic follow-up, reviewed and commented the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.