Statistics from Altmetric.com
A preterm female infant was delivered by caesarean section at 28+1 weeks of gestation because of restricted growth. She was the first twin of dichorionic diamniotic twins. Her birth weight was 0.970 kg. Her antenatal scans were all normal. She was ventilated for 5 days. The initial chest X-ray (figure 1) was consistent with moderate respiratory distress syndrome. There was a small cyst within the right lower lobe deemed insignificant at that time. She was extubated to receive non-invasive ventilation in the form of nasal intermittent positive pressure ventilation, nasal continuous positive airway pressure ventilation and heated humidified high-flow nasal cannula (HHHFNC) therapy.
While she was on HHHFNC, she developed signs of increased respiratory distress on day 39 of life. Chest X-ray (figure 2A) revealed right lower lobe pseudocystic changes.
Three days later, a contrast CT scan of the chest (figure 2B) was suggestive of congenital pulmonary airway malformation type 2 (congenital cystic adenomatoid malformation type 2) at the level of the right lower lobe.1
The case of this baby was managed conservatively. Her respiratory distress has gradually improved over a period of 4 weeks. The HHHFN was weaned off and discontinued. A repeat chest X-ray (figure 3A) showed radiological resolution of the condition. She was allowed home with no clinical signs of respiratory distress.
On regular follow-up, she continued to be asymptomatic. CT scan of the chest (figure 3B) was performed later at 10 months of age. It confirmed the radiological resolution of the condition.
Few antenatally detected cases of this condition have shown spontaneous resolution in the postnatal period.2 However, this preterm baby has presented with this condition at 5 weeks of age. Clinical and radiological resolution has occurred a month later without any surgical intervention.
Congenital pulmonary airway malformations (CPAMs) can present in premature baby several weeks after birth despite normal antenatal scans.
CPAMs may undergo spontaneous resolution after symptomatic postnatal presentation.
Conservative management may be safely considered in symptomatic patients with CPAMs.
Contributors ZGA drafted and wrote the manuscript. AA, MS and GN revised and approved the manuscript. MS prepared the images. ZGA, AA and GN treated and followed the patient.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
Patient consent for publication Parental/guardian consent obtained.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.