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Infected tooth extraction, bone grafting, immediate implant placement and immediate temporary crown insertion in a patient with severe type-B hemophilia
  1. Jose Luis Calvo-Guirado1,
  2. Georgios E Romanos2,3 and
  3. Rafael Arcesio Delgado-Ruiz4
  1. 1 International Dental Research Cathedra Department of Oral Surgery, Universidad Catolica San Antonio de Murcia Facultad de Ciencias de la Salud, Murcia, Murcia, Spain
  2. 2 Department of Periodontology, Stony Brook University, Stony Brook , New York, USA
  3. 3 Department of Oral Surgery and Implant Dentistry, Johann Wolfgang Goethe University, Frankfurt, Germany
  4. 4 Department of Prosthodontics and Digital Technology, Stony Brook University, Stony Brook, New York, USA
  1. Correspondence to Associate Professor Rafael Arcesio Delgado-Ruiz, rafael.delgado-ruiz{at}


Haemorrhagic disorders combined with soft tissue inflammation and infection may lead to severe bleeding complications before, during or after dental treatment. In selected cases, a combined therapeutic approach involving clinical therapies and systemic and local medication could improve the treatment outcomes and the patient’s quality of life. This clinical case report, presents for the first time a successful combined approach, completed in a 38-year-old male patient with severe type-B haemophilia in which an infected tooth was extracted, an immediate implant was inserted, bone grafting was performed and early implant loading was successfully applied. In addition to the clinical therapy, medication was provided orally, systemically and locally, thus preventing the haemorrhagic complications and improving the patient’s quality of life.

  • oral and maxillofacial surgery
  • haematology (incl blood transfusion)
  • drug therapy related to surgery
  • dentistry and oral medicine

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  • Contributors All the authors participated in the conception, design, analysis and interpretation of data (JLCG, GER, RAD-R). Drafting the article and revising it critically for important intellectual content (JLCG, GER, RAD-R). Final approval of the version published (JLCG, GER, RAD-R). Agreement to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved (JLCG, GER, RAD-R).

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Not required.