Article Text

Download PDFPDF
Adenovirus cerebellitis in an immunocompetent 2-year-old girl
  1. Zena Tansley-Ahmed1,
  2. Kit Wu2 and
  3. Loucas Christodoulou3
  1. 1 Department of Paediatrics, University College London Medical School, Royal Free Hospital NHS Trust, London, UK
  2. 2 Department of Neurology, King’s College Hospital NHS Trust, London, UK
  3. 3 Department of Paediatrics, Imperial College Healthcare NHS Trust, London, UK
  1. Correspondence to Dr Loucas Christodoulou, loucas{at}, loucasc{at}


Acute cerebellitis (AC) is a principal cause of acute cerebellar dysfunction in previously well children. Although the condition is usually benign, fatal complications include obstructive hydrocephalus and brainstem compression; therefore, prompt accurate diagnosis is vital.1 There are various pathogens reported in the literature as aetiological agents of AC; however, adenovirus is very rarely mentioned, with only one previous case report in the literature to the best of our knowledge.2 This case demonstrates the importance of recognising adenovirus as a cause of AC, particularly when preceded by a respiratory tract infection in the paediatric age group. Furthermore, we highlight the role of early neuroimaging in differentiating AC from other causes of acute cerebellar dysfunction, which require different management. Our patient made a full recovery with no long-term deficits demonstrating that comprehensive investigation and consideration of atypical pathogens in the context of AC is vital in securing a favourable outcome.

  • infectious diseases
  • neurology
  • infection (neurology)
  • paediatrics

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors Adenovirus is a common respiratory pathogen but is rarely found in the CSF, with only one previous case of adenovirus cerebellitis reported in the literature. Our case report aims to raise the profile of adenovirus as an important aetiological agent of acute cerebellitis in the paediatric age group and highlight the importance of early neuroimaging in ruling out other causes of acute cerebellar dysfunction and securing a favourable outcome. Each of the authors made a unique contribution to the final case report. The corresponding author, LC, supervised the project, delegated tasks accordingly and made the final amendments to each draft of the report. KW was involved in each stage of the patient’s care and thus, was able to construct a detailed case presentation. ZT-A was responsible for collating all of the relevant clinical information, alongside a full literature review of the topic, to produce a final draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.