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Primary adrenal leiomyosarcoma with inferior vena cava extension in a 70-year-old man
  1. Sai K Doppalapudi1,
  2. Tejash Shah1,
  3. Valerie A Fitzhugh2 and
  4. Vladislav Bargman1
  1. 1 Department of Urology, Rutgers- New Jersey Medical School, Newark, New Jersey, USA
  2. 2 Department of Pathology and Laboratory Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA
  1. Correspondence to Sai K Doppalapudi, sd839{at}


Primary adrenal leiomyosarcoma, a malignant soft tissue tumour originating from the smooth muscle of the inferior vena cava and adrenal vein, is rarely described in the literature. Cases are often diagnosed at an advanced stage as the tumour is not hormone-producing. We describe a 70-year-old man who presented with lower extremity swelling and abdominal varices and was subsequently found to have a large adrenal mass on imaging. Our case is among the few reported primary adrenal leiomyosarcomas in which a CT-guided biopsy was used to aid in diagnosis.

  • urological cancer
  • pathology
  • interventional radiology
  • urological surgery
  • vascular surgery

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  • Contributors SD: wrote the vast majority of the manuscript and performed a thorough literature regarding the topic, embedding a synthesis of current data in the discussion. TS: edited the manuscript and wrote the abstract for the paper. VAF: wrote the pathology-related portions of the manuscript. VB: performed the surgery, acquired next of kin consent for this case report and edited the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Next of kin consent obtained.