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Cervical carcinoma leading to orbital apex syndrome and blindness
  1. Meenakshi Wadhwani1,
  2. Swati Phuljhele2,
  3. Ritesh Kumar3 and
  4. Abdul Shameer2
  1. 1 Department of Ophthalmology, Chacha Nehru Bal Chikitsalaya, Delhi, India
  2. 2 Department of Strabismus and Neuroophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Delhi, India
  3. 3 Radiation Oncology, All India Institute of Medical Sciences, Delhi, New Delhi, India
  1. Correspondence to Dr Swati Phuljhele, drmsswati{at}


Orbit is an unusual and rare site for metastases from cancer. The most frequent site of a primary malignancy to metastasise to the orbit is the breast, followed by the lung. The malignant mixed mullerian tumour is a rare uterine and cervical carcinoma and accounts for <5% of uterine cancers. It is the primary tumour of the uterus, and de novo involvement of the cervix itself is extremely rare. We report the first case of cervical carcinoma with mixed mullerian aetiology to be associated with orbital metastasis and eventually leading to blindness and death

  • malignant disease and immunosuppression
  • cervical screening
  • visual pathway
  • pupil

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  • Contributors MW: patient primary treating ophthalmologist and manuscript design. SP: expert consultant and manuscript editing. AS: data collection. RK: treating oncologist.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.