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Unusual presentation of late-onset disseminated staphylococcal sepsis in a preterm infant
  1. Shahzad Gul Khattak,
  2. Ian Dady and
  3. Devdeep Mukherjee
  1. Neonatal Intensive Care Unit, St Mary’s Hospital, Manchester, UK
  1. Correspondence to Dr Devdeep Mukherjee, doc.devdeep{at}


An ex-30-week gestation, preterm male baby was admitted to a tertiary neonatal unit and noted to have increased ventilator requirements and diagnosed with sepsis. The baby also developed an abscess over the left elbow and over the xiphisternum along with a decrease in movement of the left hand and the right leg. Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (SA) was isolated from the blood culture. A whole body MRI showed disseminated abscess with multiple foci in the lung, left elbow and over the xiphisternum. Disseminated sepsis with multiple septic foci has not been previously reported in neonates. We would like to highlight the fact that sepsis due to PVL toxin-producing SA can cause significant morbidity and mortality in neonates. Proper screening should be done to rule out septic foci in neonates. MRI is a good non-invasive investigation to document septic foci in a neonate and rule out multiorgan involvement.

  • nosocomial infections
  • pneumonia (infectious disease)
  • neonatal intensive care
  • radiology
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  • Contributors SGK, ID and DM have been involved in patient care and patient management. SGK, ID and DM have also been involved in data collection. DM has drafted the manuscript with inputs from SGK. ID has overseen the draft of the manuscript. The final manuscript has been ratified by SGK, ID and DM.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    No grant was obtained

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Parental/guardian consent obtained.

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