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Sentinel bruising as a presentation of metastatic melanoma
  1. Lloyd Steele1,2 and
  2. Chit Cheng Yeoh3
  1. 1 Imperial College Healthcare NHS Trust, London, UK
  2. 2 Acute Medicine, Portsmouth Hospitals NHS Trust, Portsmouth, UK
  3. 3 Medical Oncology, Portsmouth Hospitals NHS Trust, Portsmouth, UK
  1. Correspondence to Dr Lloyd Steele, lloyd.steele{at}


A 46-year-old man presented with a 4-week history of bruising with subcutaneous nodules and weight loss. He also had a 2-week history of progressive back and hip pain. He had been diagnosed with stage Ib cutaneous melanoma 30 months previously, which had been fully excised. A sentinel lymph node biopsy was negative. On examination, there were five skin lesions at different stages. Each had spontaneously appeared as a bruise with a central subcutaneous nodule, and the bruising then faded to leave a persistent subcutaneous nodule. Excision of one of the nodules demonstrated a 4.5 mm diameter partly necrotic melanoma deposit in the dermis. CT scan of the head, chest, abdomen and pelvis showed widespread metastases. This rare presentation of cutaneous malignant melanoma metastases has been termed ‘sentinel bruising’. There are fewer than 10 cases reported in the literature.

  • dermatology
  • skin cancer
  • oncology
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  • Contributors LS drafted the manuscript which was critically reviewed by CCY. Both LS and CCY were involved in the clinical care of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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