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Hyperferritinaemia following intrauterine transfusions for Rh isoimmunisation
  1. Rajendra Prasad Anne,
  2. Venkataseshan Sundaram,
  3. Sourabh Dutta and
  4. Praveen Kumar
  1. Neonatology Unit, Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Praveen Kumar, drpkumarpgi{at}


Intrauterine transfusion is one of the mainstays of treatment in isoimmunised pregnancies guided by the changes in middle cerebral artery Doppler of the fetus. The common postnatal complications associated with Rh isoimmunisation are high unconjugated bilirubin requiring blood exchange transfusions, cholestasis due to bile inspissation, thrombocytopenia and anaemia. Hyperferritinaemia is an uncommon adverse effect observed in Rh isoimmunised pregnancies. In this case report, we describe the clinical course of a Rh isoimmunised neonate with hyperferritinaemia and transfusion acquired cytomegalovirus disease which resolved. Iron chelation therapy was not necessary.

  • neonatal health
  • materno-fetal medicine
  • bilirubin disorders
  • haematology (incl blood transfusion)
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  • Patient consent for publication Obtained.

  • Contributors RPA, VS and PK managed the case, conceptualised the case and written the manuscript. SD contributed with decisions in patient management. PK supervised the management, verified the manuscript and made corrections.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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