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CASE REPORT
Neurosyphilis presenting as cranial nerve palsy, an entity which is easy to miss
  1. Yoav Piura1,
  2. Yair Mina1,
  3. Orna Aizenstein2 and
  4. Avi Gadoth1
  1. 1 Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
  2. 2 Radiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
  1. Correspondence to Dr Yoav Piura, ypiura{at}gmail.com

Abstract

Neurosyphilis is a rare disease that until the 2000s was almost eradicated due to population awareness of HIV and efficient treatment. Since then, the prevalence of the entity is rising due to risk-associated behaviour such as unprotected intercourse. Neurosyphilis is still a difficult entity to diagnose especially when combined with acute HIV infection which can influence the usual clinical course of disease. In rare occasions, both acute HIV and early syphilis infection can present as mono or multiple cranial nerve palsies. This case demonstrates a rare manifestation of misdiagnosed early syphilis infection combined with acute HIV infection in a 34-year-old man with prior history of unprotected sex with men.

  • infection (neurology)
  • HIV / AIDS
  • meningitis
  • syphilis
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Footnotes

  • Patient consent for publication Obtained.

  • Contributors YP: planning, conduct, reporting, conception and design, acquisition of data, analysis and interpretation of data. YM: analysis and interpretation of data. OA: analysis and interpretation of data. AG: planning, conduct, reporting, conception and design, acquisition of data, analysis and interpretation of data.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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