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CASE REPORT
Neuroblastoma with an unusual ovarian metastasis in a 5-year-old girl
  1. Carla Steytler1,
  2. Ahmed A Darwish1,2,
  3. Sergey Popov3,
  4. Cathy Morley-Jacob4 and
  5. Daniel C Aronson1,5
  1. 1 Department of Paediatric Surgery, Noah’s Ark Children’s Hospital, University Hospital of Wales, Cardiff, UK
  2. 2 Faculty of Medicine, Ain Shams University, Cairo, Egypt
  3. 3 Department of Paediatric Radiology, Noah’s Ark Children’s Hospital, University Hospital of Wales, Cardiff, UK
  4. 4 Department of Paediatric Oncology, Noah’s Ark Children’s Hospital for Wales, University Hospital of Wales, Cardiff, UK
  5. 5 Department of Paediatric Surgery, University Children’s Hospital Zürich, Zürich, Switzerland
  1. Correspondence to Mr Ahmed A Darwish, aadarwish37{at}yahoo.co.uk

Abstract

Neuroblastoma metastasizing to the ovary is rare. We report the 10th case and review the scarce literature. A 5-year-old girl with stage M neuroblastoma presented with an upper abdominal and a pelvic mass. Evaluation after induction showed very good tumour response with three remaining localisations: two abdominal and one pelvic. At gross total resection, the pelvic mass appeared to be the enlarged and abnormal right ovary and was removed completely. Pathology showed an ovarian metastasis. On completion of her postoperative treatment, she achieved complete remission. Literature review showed that underdiagnosing of ovarian metastasis in neuroblastoma is very likely.

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Footnotes

  • Contributors All the authors have shared actively in writing the manuscript and direct patient care. They shared in the design of data, drafting, final revision and approval of the version. CS: involved in patient care, collecting data and writing the article. AD: involved in direct patient care, shared in writing and revision of the article in addition to article submission process. SP: shared in writing and revision the article. CM-J and DCA: involved in direct patient care, shared in writing and revision of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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