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Complete recovery in Wernicke’s encephalopathy complicating hyperemesis gravidarum
  1. Tripti Aneja1,
  2. Latha Chaturvedula1,
  3. Pradeep Pankajakshan Nair2,
  4. Deepak Barathi3 and
  5. Anish Keepanasseril1
  1. 1 Department of Obstetrics and Gynecology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry, India
  2. 2 Department of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
  3. 3 Department of Radiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
  1. Correspondence to Professor Latha Chaturvedula, drlathach{at}


Wernicke’s encephalopathy (WE) is an uncommon neurological complication in pregnancies complicated with hyperemesis due to thiamine deficiency. In women with hyperemesis, inadvertent glucose administration prior to thiamine supplementation triggers the development of neurological manifestations. Delay in the diagnosis can lead to maternal morbidity, and in one-third of cases may lead to persistence of some neurological deficit. With early recognition and thiamine supplementation, complete recovery is reported. We report a case of WE complicating a case of triplet pregnancy with hyperemesis gravidarum, which highlights the importance of early recognition and treatment, resulting in complete recovery as in the index case.

  • obstetrics and gynaecology
  • pregnancy
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  • Patient consent for publication Obtained.

  • Contributors TA, LC, PPN, DB and AK conceived the idea and performed the search. TA, LC and AK wrote the first draft. LC, DB and PPN reviewed and revised the final draft. AK, DB, PPN and LC reviewed and commented on the final draft.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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