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Case report
Lupus cystitis: unusual cause of renal failure in systemic lupus erythematosus
  1. Kevin John1,
  2. Krupa Varughese1,
  3. Ranil Johann Boaz2 and
  4. Tarun George1
  1. 1Internal Medicine, Christian Medical College, Vellore, Vellore, Tamil Nadu, India
  2. 2Urology, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India
  1. Correspondence to Dr Tarun George; tarunkg{at}


A 42-year-old woman presented with chronic fever, abdominal pain, intermittent loose stools and dysuria for 3 months. She had recently developed acute dyspnoea with acute kidney injury. She was found to have a contracted, thick-walled bladder with bilateral hydroureteronephrosis. She underwent bilateral percutaneous nephrostomies, following which her renal function recovered. She satisfied the clinical and immunological features of the Systemic Lupus International Collaborating Clinics criteria for systemic lupus erythematosus (SLE). She was initiated on immunosuppression. Lupus cystitis with a contracted bladder is an uncommon presentation of SLE.

  • systemic lupus erythematosus
  • acute renal failure
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  • Contributors KJ and KV conceived, designed and drafted the manuscript. RJB was the urologist who was involved in patient care. TG was the medicine consultant involved in patient care. Both RJB and TG reviewed the manuscript. TG gave the final approval for the manuscript prior to submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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