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Case report
Iatrogenic cerebral abscess leading to resolution of severe delusional disorder
  1. Conor SN Gillespie1,2 and
  2. Catherine J McMahon1
  1. 1 Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, UK
  2. 2 School of Medicine, University of Liverpool, Liverpool, UK
  1. Correspondence to Conor SN Gillespie; hlcgill2{at}


A cerebral abscess (focal infection of brain parenchyma) carries a high mortality and morbidity. Iatrogenic cerebral abscesses are less common and make up 10% of all cases. The presence of a cerebral abscess can rarely improve a patient’s prognosis and quality of life, however this case illustrates an abscess and its treatment following a prolonged course of antibiotics leading to resolution of a severe psychotic disorder. This is a case report of a 32-year-old female inpatient at a psychiatric hospital with a long-standing history of congenital hydrocephalus, cerebral palsy and organic delusional disorder who developed an iatrogenic cerebral abscess after insertion of an implantable intracranial pressure monitoring device. After receiving treatment of 6 weeks of intravenous meropenem the patient’s mental condition rapidly improved, she became stable and euthymic and was discharged home. The patient has since had no delusions or hallucinations and is living independently at home.

  • neurosurgery
  • psychiatry
  • delusional disorder
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  • Contributors Conception and design; analysis and interpretation of data; drafting the article; critically revising the article: CJM, CSNG. Acquisition of data: CSNG. Supervision by CJM. Patient was under the care of CJM. All authors agree with the final version of the submitted manuscript. CSNG is the lead author and guarantor.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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