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Case report
Association of Mondor's disease with oral contraceptive pills
  1. Mohammed AlSheef1,
  2. Hana A Aboauf2,
  3. Abdul Rehman Zia Zaidi1 and
  4. Isamme AlFayyad3
  1. 1 Medical Specialties Department, King Fahad Medical City, Riyadh, Saudi Arabia
  2. 2 Ophthalmology, Ohoud Hospital, Medina, Saudi Arabia
  3. 3 Research Center, King Fahad Medical City, Riyadh, Saudi Arabia
  1. Correspondence to Dr Mohammed AlSheef; malsheef{at}


Mondor's disease (MD) is a rare disease characterised by thrombophlebitis of superficial veins in the body. We describe a case of a 28-year-old woman with a painful cord-like lesion of the right breast (3 cm) overlying the right upper quadrant. The patient was recently prescribed metformin and oral contraceptive pills for symptomatic polycystic ovarian syndrome. Right breast ultrasound showed a tubular anechoic structure with several areas of narrowing, resembling a beaded appearance. The patient was diagnosed with MD associated with use of oral contraceptive pills. We recommended the patient to discontinue oral contraceptive because discontinuation of the causative drug is important. The patient was started on topical non-steroidal anti-inflammatory drugs and a therapeutic dose of enoxaparin. The patient showed significant clinical improvement after 5 days. At 6-week outpatient follow-up, complete resolution of the disease was noted.

  • general practice/family medicine
  • haematology (incl blood transfusion)

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  • Contributors All authors contributed to the writing of this manuscript. MAS and HAA wrote the case description, ARZZ wrote the introduction and IAF wrote the discussion. All the authors proofread, reviewed and approved the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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