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Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
Case report
New-onset asthma in a bilateral lung transplant patient
  1. Daniel Benjamin Fyenbo,
  2. Kristine Bruun Degn,
  3. Johannes Martin Schmid and
  4. Elisabeth Bendstrup
  1. Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark
  1. Correspondence to Dr Daniel Benjamin Fyenbo; daniel.fyenbo{at}gmail.com

Abstract

We present a case of new-onset asthma in a 35-year-old man who had undergone bilateral lung transplantation 11 years before due to idiopathic bronchiectasis and pulmonary hypertension. He presented with recurrent episodes of breathlessness, wheezing and coughing. Spirometry demonstrated severe airway obstruction. After treatment with systemic and inhaled corticosteroids and long-acting bronchodilators as well as short-acting beta-agonists as needed, his symptoms resolved and his spirometry normalised. A bronchial mannitol challenge test showed significant airway hyperresponsiveness and is thus consistent for a diagnosis of asthma. To our best knowledge, this is the first case of late new-onset asthma in a lung transplant recipient.

  • asthma
  • respiratory medicine

https://doi.org/10.1136/bcr-2019-231654

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    Footnotes

    • Contributors All authors (DBF, KBD, JMS and EB) designed the work of the case report. KBD, JMS and EB collected data, while DBF contributed with analysis and interpretation of data (with supervision from KBD, JMS and EB). DBF drafted the case report and KBD, JMS and EB critically revised the draft. All authors are in agreement with the content of this final version of the case report.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.