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Case report
Pancreatic metastases to the colon: an unusual cause of colonic obstruction
  1. Deborah Yae-jung Park1,
  2. Smitha Krishnamurthi2,
  3. Prabhleen Chahal3,
  4. Erinn Downs-Kelly4 and
  5. Gareth Morris-Stiff5
  1. 1 Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio, USA
  2. 2 Hematology and Medical Oncology, Cleveland Clinic, Cleveland, Ohio, USA
  3. 3 Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, Ohio, USA
  4. 4 Department of Anatomic Pathology, Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
  5. 5 Hepato-Pancreato-Biliary Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, Ohio, USA
  1. Correspondence to Dr Gareth Morris-Stiff, garethmorrisstiff{at}


We report a case of a 73-year-old woman who developed pancreatic adenocarcinoma and presented with a colonic obstruction due to isolated metastasis to the colon, the primary lesion being diagnosed subsequently on imaging. The histopathological findings of the pancreatic mass exhibited a morphology and immunohistochemical profile consistent with a pancreatic adenocarcinoma and led to further analysis of the colonic pathology which ultimately confirmed the lesion was a pancreatic metastases rather than a primary colonic carcinoma. As the pancreatic cancer had metastasised to the colon, it was inoperable. The patient continued on palliative chemotherapy and passed 7 months after presentation for evaluation of her pancreatic mass due to progression of the pancreatic cancer. This report demonstrates a rare presentation of pancreatic cancer with colonic obstruction due to isolated metastatic disease and illustrated the importance of careful evaluation of histopathological findings.

  • pancreatic cancer
  • colon cancer
  • pancreas and biliary tract
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  • Contributors DY-jP performed the background research and wrote the paper. GM-S, SK, PC and ED-K reviewed and performed the final editing of the paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Patient consent for publication Obtained.

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