Dofetilide is a class III antiarrhythmic drug that has proven efficacious in maintaining sinus rhythm in up to 60% of patients with persistent atrial fibrillation. Dofetilide’s most concerning adverse effect is QT prolongation and polymorphic VT, but providers should be aware of other rare significant side effects. We report a case of dofetilide associated Bell’s palsy masquerading as stroke that developed shortly after a cardioversion. The patient’s facial weakness, a side effect of dofetilide, resolved relatively quickly after discontinuation of the medication and a short course of oral corticosteroids.
- cardiovascular system
- cranial nerves
- pacing and electrophysiology
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Contributors LZ is responsible for writing the manuscript, obtaining patient consent and providing initial patient care and follow-up. DS is responsible for a supervisory role, revisions of the manuscript and providing initial and follow-up care to the patient.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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