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Gross anterior segment ischaemia following vitreoretinal surgery for sickle-cell retinopathy
  1. Andrew Walkden1,
  2. Benjamin Griffin2,
  3. Clarissa Cheng3 and
  4. Felipe Dhawahir-Scala1
  1. 1 Vitreo-retinal Unit, Manchester Royal Eye Hospital, Manchester, UK
  2. 2 Manchester University NHS Foundation Trust, Manchester Royal Eye Hospital, Manchester, UK
  3. 3 Ophthalmology, Tan Tock Seng Hospital, Singapore
  1. Correspondence to Dr Benjamin Griffin, benjamin.griffin{at}


We report the case of a 32-year-old Afrocaribbean man with known stage 3 proliferative sickle-cell retinopathy who presented with a mixed picture of tractional and rhegmatogenous macula off detachment. He underwent left primary 25 g vitrectomy with silicone oil, delamination and endolaser photocoagulation under a general anaesthetic. He, however, presented 48 hours postoperatively with gross anterior segment ischaemia. His pain and ocular signs settled over the course of a few days following administration of supplemental oxygen, oral steroids, analgesia and intravenous hydration. Examination showed resolution of his proptosis and orbital signs as well as anterior segment inflammation. He remains under follow-up.

  • ophthalmology
  • anterior chamber
  • retina
  • sickle cell disease

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  • Contributors All four authors, AW, BG, CC and FDS, have met or reviewed the patient in a professional setting related to his clinical care and were involved in the conception and design of this report. All authors contributed significantly to the writing of this case report and gave final approval of the version published. All agree to be accountable for the article and to ensure that all questions regarding accuracy or integrity of the article are investigated and resolved as stipulated by the ICMJE recommendations 2013. Furthermore, each author is able to identify which co-authors are responsible for specific other parts of the work however, also have confidence in the integrity of the contributions of their co-authors. There are no other individuals who fulfil the above criteria.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.