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SAPHO syndrome with enthesopathy
  1. Chin-Fang Su1,2,
  2. Yu-Chuan Shen3,
  3. Hsien-Tzung Liao1,2 and
  4. Chang-Youh Tsai1,2
  1. 1 Division of Allergy, Immunology & Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
  2. 2 Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan
  3. 3 Division of Rheumatology, Tao-Yuan General Hospital, Ministry of Health & Welfare, Tao-Yuan, Taiwan
  1. Correspondence to Professor Chang-Youh Tsai, cytsai{at}


Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome was first described as chronic recurrent multifocal osteomyelitis. Because of its rarity, a thorough description of its clinical manifestations is lacking. Herein, we describe the clinical manifestations and imaging features, especially the enthesopathy in bilateral Achilles tendons, of a middle-aged Asian woman with SAPHO syndrome, who improved after diclofenac treatment.

  • musculoskeletal syndromes
  • radiology (diagnostics)
  • musculoskeletal and joint disorders
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  • C-FS and Y-CS contributed equally.

  • Contributors C-FS rewrote this manuscript and Y-CS prepared these materials. H-TL provided the pertinent clinical and laboratory data and C-YT supervised the whole study.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

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