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Takotsubo cardiomyopathy triggered by status epilepticus: case report and literature review
  1. Savvy Nandal,
  2. Anastasia Castles,
  3. Muhammad Asrar ul Haq and
  4. William van Gaal
  1. Department of Cardiology, The Northern Health, Epping, Victoria, Australia
  1. Correspondence to Dr Savvy Nandal, savvy.nandal{at}


Takotsubo cardiomyopathy (TC) is acute stress-induced cardiomyopathy with characteristic transient wall motion abnormalities. TC has a clinical presentation similar to an acute coronary syndrome, including chest pain or dyspnoea, ECG changes and elevated cardiac enzymes. TC often occurs after emotional stress. There are approximately 50 TC cases reported related to seizure activity, and our review revealed 15 articles which were associated with status epilepticus. This condition can be a serious complication of seizures. We report a case of TC after status epilepticus in a patient who had been seizure-free for 20 years.

  • cardiovascular medicine
  • epilepsy and seizures
  • clinical diagnostic tests

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  • Contributors All authors contributed significantly to the planning, conduct and reporting of the manuscript. SN was the first author of the manuscript, reviewed the patient’s case notes and made revisions. AC and AAH reported the angiogram findings and reviewed and amended the manuscript. WG was the project supervisor and reviewed and amended the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.