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Adipsic diabetes insipidus secondary to craniopharyngioma resection
  1. María Alejandra Pérez1,2,
  2. Henry Augusto Millán1,
  3. Julián Alberto Naranjo2 and
  4. Andrés Flórez Romero3
  1. 1 Internal Medicine, Fundación Cardioinfantil, Bogotá, Colombia
  2. 2 Internal medicine, Fundación Cardioinfantil, Bogotá, Colombia
  3. 3 Fundación Cardioinfantil Instituto de Cardiologia, Bogotá, Colombia
  1. Correspondence to Dr María Alejandra Pérez, mariaperezardila{at}


Adipsic diabetes insipidus is an infrequent disease which may be associated with craniopharyngioma. It may be secondary to the tumour’s extension, as well as to resection of the mass. We present the case of a 24-year-old woman with a history of delayed puberty and hypothyroidism, but no prior study reports. She consulted due to a headache with warning signs associated with altered visual acuity. Brain MRI was performed which showed signs of a non-adenomatous lesion with suprasellar and hypothalamic extension. Following transcranial surgery, she developed diabetes insipidus criteria, with absence of thirst documented during the hospitalisation. The histopathological findings confirmed the diagnosis of craniopharyngioma. The patient was treated with desmopressin and received recommendations regarding rehydration according to the quantification of losses, with electrolyte stabilisation.

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  • Contributors MAP and JAN contributed to the article in the drafting of the background, case report (differential diagnoses, treatment, outcome) as well as in the writing of the discussion. HAM and AFR contributed in the writing of discussion and key messages. All the authors reviewed the full article and made changes in writing, grammar and spelling.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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