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Tumour in a tumour: a well-differentiated spindle cell sarcoma within a forearm lipoma
  1. James C. R. Wadkin1,
  2. Sebastian Senes2,
  3. Scott Evans3 and
  4. Jonathan Stevenson3
  1. 1 Kingston Hospital NHS Foundation Trust, Kingston upon Thames, UK
  2. 2 Department of Orthopaedics, Hospital Britanico de Buenos Aires, Buenos Aires, Argentina
  3. 3 Department of Orthopaedic Oncology and Arthroplasty, Royal Orthopaedic Hospital, Birmingham, UK
  1. Correspondence to Dr James C. R. Wadkin, james.wadkin1{at}


Lipomas are common, benign, soft tissue masses in adults. Sarcomatous change within a giant lipoma is a very rare event. We present a case of a woman presenting with a forearm lipoma that subsequently developed a central, well-differentiated, spindle-cell sarcoma within the lipoma. This case underlines the importance of identifying red flags for referral of soft tissue tumours.

  • cancer intervention
  • oncology
  • orthopaedics
  • orthopaedic and trauma Surgery
  • surgical oncology

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  • Contributors JS, SE and SS: conceived and designed research; JCW: drafted the manuscript and prepared figures; JS and SE: edited and revised manuscript and approved final version of manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.