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Management of hypertriglyceridaemic pancreatitis in the acute setting and review of literature
  1. Suhaniya Samarasinghe1,
  2. Parizad Avari2,
  3. Karim Meeran2 and
  4. Jaimini Cegla2
  1. 1 Department of Endocrinology, Northwick Park Hospital, London, UK
  2. 2 Division of Diabetes Endocrinology and Metabolism, Faculty of Medicine, Imperial College London, London, UK
  1. Correspondence to Dr Suhaniya Samarasinghe, snss106{at}


Acute pancreatitis (AP) is a potentially life-threatening complication of severe hypertriglyceridaemia, which is the third most common cause of AP after gallstone disease and alcohol excess. Standard therapy involves the use of lipid-lowering agents, low-molecular-weight heparin and insulin infusion. In some cases, when standard medical therapies fail, non-pharmacological methods based on the removal of triglycerides with therapeutic plasma exchange can provide positive results in the acute phase. There are currently no guidelines covering management in the acute phase, however, these approaches should be considered in severe or very severe hypertriglyceridaemia. Here, we report the case of a 37-year-old man with recurrent AP due to hypertriglyceridaemia and review the literature.

  • endocrine system
  • lipid disorders
  • pancreatitis

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  • Contributors SS and PA involved in conception, design and planning. Acquisition of data and organising attendance for signed patient consent form done by SS. SS and PA drafted the article and SS, PA, KM and JC revised it. KM and JC also helped with data analysis and interpretation of data.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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