A 24-year-old man with previous matched unrelated donor allogenic bone marrow transplant for aplastic anaemia and chronic graft versus host disease on steroid taper presented with progressively worsening anasarca. CT revealed large pericardial effusion, while echocardiogram was concerning for early tamponade physiology. He underwent emergent pericardiocentesis with pericardial drain placement. Extensive rheumatological and infectious work-up was unrevealing with patient’s presentation attributed to pericardial graft versus host disease. This highlights the need of physicians to be aware of pericardial serositis as a complication of graft versus host disease due to its life-threatening complications, which require immediate intervention.
- pericardial disease
- haematology (incl blood transfusion)
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Patient consent for publication Obtained.
Contributors KN involved in managing the patient, writing parts for the final version of the manuscript and has read and approved the final version submitted. KJ involved in managing the patient, writing parts for the final version of the manuscript, has read and approved the final version submitted and participated in submission process. ES involved in managing the patient, writing parts for the final version of the manuscript and has read and approved the final version submitted, and completed submission process.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
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