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IgA nephropathy with diffuse alveolar haemorrhage
  1. Shinichi Miyazaki1,
  2. Akiko Hattori2,
  3. Yasumasa Kuno1 and
  4. Takuya Ikeda1
  1. 1 Department of Pulmonary Medicine, Yokkaichi Municipal Hospital, Yokkaichi, Japan
  2. 2 Department of Nephrology, Yokkaichi Municipal Hospital, Yokkaichi, Japan
  1. Correspondence to Dr Shinichi Miyazaki, miyazaki.sin1{at}


Immunoglobulin (Ig)A nephropathy is the most common cause of primary glomerulonephritis worldwide. While IgA nephropathy has been associated with a variety of other diseases, pulmonary complications are extremely rare. A 58-year-old man presented with a 2-week history of fever and exertional dyspnoea. A chest imaging revealed bilateral consolidation predominantly in upper lungs. Laboratory findings showed elevated serum creatinine with proteinuria and haematuria. Flexible bronchoscopy revealed diffuse alveolar haemorrhage, and IgA nephropathy was confirmed on a renal biopsy. He received prednisone with good effect. This case highlights the need to consider IgA nephropathy in the differential diagnosis of pulmonary renal syndrome.

  • acute renal failure
  • respiratory medicine

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  • Patient consent for publication Obtained.

  • Contributors SM: reviewed the patient, performed the literature review and wrote the manuscript. AH: involved in critical revision of the work. YK and TI: supervised the project.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.