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Corynebacterium striatum prosthetic valve endocarditis with severe aortic regurgitation successfully treated with transcatheter aortic valve replacement
  1. Syed Yaseen Naqvi1,
  2. Ibrahim G Salama2,
  3. Craig Narins1 and
  4. Thomas Stuver1
  1. 1 Department of Medicine, Division of Cardiology, University of Rochester Medical Center, Rochester, New York, USA
  2. 2 Department of Internal Medicine, Unity Hospital, Rochester, New York, USA
  1. Correspondence to Dr Syed Yaseen Naqvi, syedalinaqvi1{at}


We describe the case of a 69-year-old man with a history of bioprosthetic aortic valve replacement who presented with Corynebacterium striatum prosthetic valve endocarditis (PVE) complicated by severe aortic insufficiency with refractory cardiogenic shock despite antibiotic therapy. He was considered a prohibitive-risk surgical candidate due to co-morbid conditions and off-label valve-in-valve transcatheter aortic valve replacement (TAVR) was performed after detailed multidisciplinary evaluation. He recovered well without recurrent infection following completion of antibiotics and transthoracic echocardiogram at 12 months showed a normal functioning prosthetic valve. To our knowledge, this is the first reported case of native or PVE treated with TAVR.

  • interventional cardiology
  • valvar diseases

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  • Contributors SYN and IGS wrote the case. CN edited the case. TS edited the case and was the physician responsible for the patient care.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.