Article Text
Abstract
Rhabdomyolysis is characterised by muscle breakdown with release of damaging proteins that can have devastating consequences. Acute influenza infection is being increasingly recognised as an underlying aetiology. We report an unusual case of severe rhabdomyolysis with acute renal failure due to influenza A infection that improved with high-dose oseltamivir and intravenous fluids. In our case, we also noticed a temporal relation between fever spikes and subsequent increase in serum creatine kinase. The precise mechanism between the rise in temperature and creatine kinase is unclear but it could be due to direct viral invasion of myocytes or due to release of new viral progeny following replication in the myocyte.
- drugs: infectious diseases
- influenza
- adult intensive care
- acute renal failure
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Footnotes
Contributors All authors have contributed significantly to the final product of this article. All authors were part of the patient’s clinical care while in the hospital, contributed to the planning, data gathering, literature review, writing, editing and analysing the article. All authors have fulfill the criteria as defined by BMJ pertaining to authorship and all authors have approved the final version of this article.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent Not required.
Provenance and peer review Not commissioned; externally peer reviewed.