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CASE REPORT
Acute disseminated encephalomyelitis: complication of a vaccine preventable disease
  1. Arundhati Banerjee1,
  2. Renu Suthar2,
  3. Sameer Vyas3 and
  4. Mini P Singh4
  1. 1 Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical education and Research, Chandigarh, Chandigarh, India
  2. 2 Pediatric Neurology Unit, Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India
  3. 3 Department of Radiodiagnosis and imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  4. 4 Department of Virology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Renu Suthar, drrenusuthar{at}gmail.com

Abstract

Acute disseminated encephalomyelitis (ADEM) is a rare inflammatory-demyelinating disease of central nervous system. Several viral infections and vaccines act as precipitating factor for ADEM. We report an 8-year-old girl presenting with acute-onset flaccid paraparesis and bilateral painless vision loss. MRI brain showed extensive multifocal patchy demyelination and she made good clinical recovery with steroids and intravenous immunoglobulin therapy. She had history of bilateral parotid swelling before the onset of neurological symptoms and diagnosis of mumps was confirmed by positive ELISA in serum. Mumps, usually a benign and self-limited viral infection, rarely can cause severe neurological complications. Hence, we report this case to emphasise the importance of mumps vaccination and the need to strengthen the health policy system for the prevention of disease.

  • infection (neurology)
  • neuroimaging
  • vaccination/immunisation
  • paediatrics

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Footnotes

  • Contributors AB: clinical management and preparation of manuscript. RS: patient management and clinical incharge, revision and final approval of manuscript. SV: radiology input. MPS: virology assay.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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