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Unusual association of diseases/symptoms
Two malignant tumours in the anterior mediastinum positive for CD5
  1. C M Steger1,
  2. A Morresi-Hauf2,
  3. J Krugmann3,
  4. P Schirmacher4,
  5. R J Rieker3,4,
  6. G Mechtersheimer4
  1. 1Department of Cardiac Surgery, Medical University Innsbruck, Austria
  2. 2Department of Pathology, Asklepios Fachkliniken Gauting, Germany
  3. 3Department of Pathology, Medical University Innsbruck, Austria
  4. 4Department of Pathology, University Hospital Heidelberg, Germany
  1. Correspondence to C M Steger, Christina.M.Steger{at}i-med.ac.at

Summary

To our knowledge, the simultaneous involvement of the anterior mediastinum by a thymic carcinoma and a B-cell chronic lymphocytic leukaemia has not been reported previously. The authors describe the case of a 62-year-old man, suffering from severe bronchitis. Chest x-ray and CT scan showed a mediastinal tumour, resected short-time after diagnosis. First, standard based histological examination revealed a thymic carcinoma admixed by a dense lymphatic infiltrate. Additional immunohistochemical staining for CD5-labelled epithelial thymic carcinoma cells as well as neoplastic B cells and led in combination with blood tests to confirm the diagnosis of the composite occurrence of a thymic carcinoma and a B-cell chronic lymphocytic leukaemia.

https://doi.org/10.1136/bcr.09.2009.2289

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    Footnotes

    • Competing interests None.