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Life-threatening rupture of interstitial ectopic pregnancy: a rare presentation of metastatic invasive mole
  1. Joana Figueiredo1,
  2. Ana Tomé1,
  3. Patrícia Nazaré1 and
  4. Sofia Carralas Antunes2
  1. 1Department of Gynecology and Obstetrics, Hospital Garcia de Orta EPE, Almada, Portugal
  2. 2Department of Pathology, Hospital Garcia de Orta EPE, Almada, Setúbal, Portugal
  1. Correspondence to Dr Joana Figueiredo; joana.mra.figueiredo{at}gmail.com

Abstract

An invasive mole is an uncommon type of gestational trophoblastic disease, and if considering its implantation in an interstitial extrauterine location, we are facing a rarer condition.

There are 14 cases described of interstitial ectopic gestational trophoblastic disease. As far as we know, we present the third case of invasive mole within interstitial location, in this case with pulmonary metastases.

The diagnosis of an interstitial implantation is challenging. Our patient was initially diagnosed with an intrauterine hydatidiform molar pregnancy, and a uterine aspiration was performed. Two weeks later, she presented with haemodynamical instability due to a severe haemoperitoneum. A laparotomy was immediately performed and revealed a ruptured interstitial pregnancy with molar vesicle extrusion. Besides its rarity, we highlight the clinical presentation with hypovolaemic shock due to rupture of ectopic pregnancy in a young nulliparous woman, which required an emergent surgical approach with lifesaving purpose while preserving future fertility.

  • Gynecological cancer
  • Chemotherapy

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Footnotes

  • Contributors JF and AT conceived of the presented idea. JF developed the theory and performed the computations. AT and PN had verified the analytical methods. SCA was responsible for histopathological analysis and revision of the case. All authors discussed the results and contributed to the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.