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Case report
Extensive cerebral venous sinus thrombosis: a potential complication in a patient with COVID-19 disease
  1. Paul Bolaji,
  2. Babatunde Kukoyi,
  3. Nasar Ahmad and
  4. Chris Wharton
  1. Stroke Medicine, New Cross Hospital, Wolverhampton, UK
  1. Correspondence to Dr Paul Bolaji; paul.bolaji{at}nhs.net

Abstract

A 63-year-old man was admitted with left-sided weakness and subsequent focal seizures following a recent diagnosis of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in a nearby hospital. He developed status epilepticus and became comatose, requiring intensive care unit admission for invasive ventilation. Imaging done at admission confirmed extensive cerebral venous sinus thrombosis (CVST) with bilateral venous cortical infarcts and acute cortical haemorrhage. No known risk factor for CVST could be identified. He improved with anticoagulation and antiepileptic therapy. He was subsequently transferred to an inpatient rehabilitation facility. Although Coronavirus disease 19 (COVID-19) infection has been previously associated with thrombotic complications, these mostly relate to the pulmonary vasculature. We present this case as a potential association between CVST and COVID-19 infection.

  • infections
  • stroke

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Footnotes

  • Contributors PB: managed the patient, conceived the idea of the case report, was involved in planning, literature search and referencing for the case report, wrote the initial draft of the case report, revised the case report and approved the final draft of the case report; is the guarantor. BK: managed the patient, conceived the idea of the case report, was involved in planning the case report, wrote the initial draft of case report, took consent from the patient, revised the case report and approved the final draft of the case report. NA: managed the patient, was involved in planning the case report, revised, critically analysed the initial draft, did literature search and approved the final draft of the case report. CW managed the patient, was involved in planning the case report, revised, critically analysed the initial draft and approved the final draft of the case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.