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CASE REPORT
Ischaemic stroke as initial presentation of systemic malignancy
  1. Stephan Goedee1,2,
  2. Alike Naber3,
  3. Jörgen M P Rovers4,
  4. Gerwin Roks4
  1. 1Department of Neurology, UMC Utrecht, Utrecht, The Netherlands
  2. 2Brain Center Rudolf Magnus, Department of Neuroscience, UMC Utrecht, Utrecht, The Netherlands
  3. 3Department of Internal Medicine, St Elisabeth Hospital, Tilburg, The Netherlands
  4. 4Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands
  1. Correspondence to Stephan Goedee, stephangoedee{at}gmail.com

Summary

Ischaemic stroke as the initial presentation of systemic malignancy is reported infrequently and is characterised by ischaemic lesions that exceed the vascular territory of a single vessel. There is also a high rate of early stroke recurrence. Several pathophysiological mechanisms are known to cause cerebrovascular complications in malignancies, as a direct effect of the tumour, paraneoplastic or even of the tumour treatment itself. Prognosis is reportedly poor, treatment is symptomatic and at best anecdotal. We present a case report and available literature.

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