Abstract
A 64-year-old man, resident in Arizona for 3 years, presented with a week-long history of a dry cough and 'flu-like symptoms'. He had recently been renovating his house. A chest radiograph showed a left mid-zone opacity. Investigations for lung cancer were performed and he underwent CT-guided biopsy of the lesion. A coccidioidal fungus known to cause 'Valley Fever' was isolated. Treatment with fluconazole led to a complete recovery. This fungal infection is endemic in parts of the USA and Mexico and usually presents with respiratory symptoms. Additional complications include disseminated disease and meningitis.
MeSH terms
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Antifungal Agents / therapeutic use
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Arizona / epidemiology
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Coccidioides / isolation & purification*
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Coccidioidomycosis / diagnosis*
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Coccidioidomycosis / diagnostic imaging
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Coccidioidomycosis / drug therapy
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Coccidioidomycosis / microbiology
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Cough / microbiology*
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Fluconazole / therapeutic use
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Humans
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Lung / diagnostic imaging
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Lung / microbiology*
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Lung Diseases, Fungal / diagnosis*
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Lung Diseases, Fungal / diagnostic imaging
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Lung Diseases, Fungal / drug therapy
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Lung Diseases, Fungal / microbiology
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Male
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Middle Aged
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Radiography, Thoracic
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Travel
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Treatment Outcome
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United Kingdom / epidemiology
Substances
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Antifungal Agents
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Fluconazole