Symptomatic hyperthyroidism in metastatic testicular mixed germ cell tumour

BMJ Case Rep. 2018 Jun 8:2018:bcr2018224877. doi: 10.1136/bcr-2018-224877.

Abstract

This is a case of a young 34-year-old man who had symptomatic hyperthyroidism from an extremely high serum beta HCG level in the setting of a metastatic stage IIIC mixed germ cell tumour. The patient's thyroid function normalised with treatment of the cancer as the beta HCG levels declined.

Keywords: thyroid disease; urological cancer.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bleomycin / therapeutic use
  • Chemoradiotherapy
  • Chorionic Gonadotropin, beta Subunit, Human / blood*
  • Cisplatin / therapeutic use
  • Etoposide / therapeutic use
  • Humans
  • Hyperthyroidism / etiology*
  • Hyperthyroidism / metabolism
  • Male
  • Neoplasm Metastasis
  • Neoplasms, Germ Cell and Embryonal / diagnostic imaging*
  • Neoplasms, Germ Cell and Embryonal / metabolism
  • Neoplasms, Germ Cell and Embryonal / therapy*
  • Orchiectomy
  • Testicular Neoplasms / diagnostic imaging*
  • Testicular Neoplasms / metabolism
  • Testicular Neoplasms / therapy*
  • Treatment Outcome

Substances

  • Chorionic Gonadotropin, beta Subunit, Human
  • Bleomycin
  • Etoposide
  • Cisplatin

Supplementary concepts

  • Testicular Germ Cell Tumor